Ki-67 Antigen Expression in Hepatocellular Carcinoma Using Monoclonal Antibody MIB1:A Comparison With Proliferating Cell Nuclear Antigen
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چکیده
منابع مشابه
Assessment of cell proliferation in hydatidiform mole using monoclonal antibody MIB1 to Ki-67 antigen.
AIMS To assess the role of Ki67 immunoreactivity in predicting the clinical progress of hydatidiform mole. METHODS Tissue from 87 hydatidiform moles, 11 normal first trimester placentas, 11 normal term placentas and 17 spontaneous abortions were examined for expression of Ki67 antigen, using the monoclonal antibody MIB1. RESULTS Ki67 immunoreactivity was significantly higher in the tissue f...
متن کاملProliferating cell nuclear antigen expression in papillary thyroid carcinoma.
AIMS To correlate the expression of proliferating cell nuclear antigen (PCNA) with various clinicopathological features of papillary thyroid carcinoma. METHODS Sections from 131 formalin fixed, paraffin wax embedded papillary thyroid carcinomas were stained with a monoclonal antibody (PC10) directed against PCNA using the avidin-biotin immunoperoxidase (ABC) method. PCNA immunoreactivity was ...
متن کاملMeasurement of Ki-67 antigen in 159 pituitary adenomas using the MIB-1 monoclonal antibody.
Pituitary adenomas sometimes show rapid growth and recurrence, and about one third invade the structures surrounding the sella turcica. In an attempt to determine aggressive behavior at an early stage, we used the MIB-1 antibody to identify the Ki-67 antigen. The present study was designed to evaluate pituitary adenomatous tissue in terms of secretion and proliferation and to correlate the Ki-6...
متن کامل[Expression of nuclear Ki-67 antigen in prostatic high grade intraepithelial neoplasia and prostatic carcinoma].
BACKGROUND/AIM Prostatic intraepithelial high grade neoplasia (PINHG) is accepted as preneoplastic lesion in prostatic carcinoma. One of the fundamental events in early oncogenesis is the disruption of proliferative activity. One of the numerous regulatory proteins is Ki-67 expressed in all proliferating cells. Index Ki-67 is considered to have prognostic significance. The aim of the study was ...
متن کاملProliferating Cell Nuclear Antigen (PCNA) in Prostatic Carcinoma
Proliferating cell nuclear antigen (PCNA) is an auxiliary protein of DNA • @polymerase-• Ý • @ that • @is • @ synthesized • @ during • @ the • @ late • @G1 • @ phase through the S phase of cell proliferation. The expression of PCNA correlates strongly with cell proliferation. In the present study, employing NC-012, which is an anti-human PCNA monoclonal antibody, we performed immunohistochemica...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 1995
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/104.3.313